This 90-card set features original artwork produced from the Legendary Marvel Deck-Building Game (see "'Marvel Legendary'"). It has several serial numbered parallels that showcase Spider-Man characters like Green Goblin, Hobgoblin, Ghost-Spider, and more. Variants include comic cover cards, Plexiglass cards, Metal cards, and numbered Artist Autograph cards. There are also randomly inserted Marvel Universe Impel cards in the pack.

Boxes have 4 Legendary Responsibility cards, 2 Spider-Man Corner Box cards, 5 Serial-numbered cards, and an additional insert or Chase Hit card in them. Each box comes with 12 packs, and the packs have 7 cards.