This chart of the Top 5 Roleplaying Games (hobby channel) reflects sales in Spring 2021 (January-April).  The charts are based on interviews with retailers, distributors, and manufacturers.

ICv2's Top 5 Roleplaying Games – Spring 2021

Rank

Franchise

Publisher

1

Dungeons & Dragons

Wizards of the Coast

2

Cyberpunk

R. Talsorian

3

Pathfinder

Paizo

4

Alien

Free League Publishing

5

5E – Compatible

Various

These bestseller lists are from ICv2's Internal Correspondence #100:

For the lists of the bestselling Collectible Games in the hobby channel, mass channel, and overall, click here.
For the bestselling Board Games in the hobby channel, click here.
For the bestselling Card/Dice Games in the hobby channel, click here.
For the bestselling hobby channel Non-Collectible Miniature lines, click here.

For more on hobby game sales in the Spring season, and info on how to get your copy of ICv2's Internal Correspondence, with the full market reports, charts, Pick Hits, and reviews, see "Hobby Game Sales Sprout in Spring 2021."