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Each player begins the Heroes Unite game with a basic 10-card deck. "Power" is the currency of value in this game as players attempt to acquire new stronger cards to add to their decks. The goal of a deck-building game is to craft a personalized deck into a well-oiled machine. Five different types of cards can be acquired including "Villains," "Heroes," "Equipment," "Super Powers," and "Locations."
A large, central stack of cards supplies a five-card “Line-Up” from which players make their purchases. Each player will always have five face-up cards to choose from each turn, so every turn there are new options and surprises.
When a player has amassed enough Power, he or she may defeat the current Super-Villain, but when a Super-Villain is defeated, a new one appears and makes an Attack against each player in the game. Players can defend themselves by using cards such as "Force Field" and "Helmet of Fate."
The player who ends up with the most "Victory Points" from the cards in his or her deck is the winner.