Marvel Studios head Kevin Feige has explained how the first 22-movie arc in the Marvel Cinematic Universe will end, and how the storylines connect with the Spider-Man movies.   The explanation came in an interview with the Toronto Sun, in response to questions about the Sony movies featuring Marvel characters.

Feige explained that Spider-Man:  Homecoming, opening this weekend, is part of a five-movie storyline for the character:  Civil War, Homecoming, Avengers Infinity War, untitled Avengers, Spider-Man:  Homecoming 2.

The untitled Avengers movie, which is planned for May of 2019, will actually complete the initial 22-movie story arc for the Marvel Cinematic Universe.

Spider-Man:  Homecoming 2, which is planned for July of 2019, two months later, will then “usher us into the aftermath and how things proceed for there,” Feige told the Sun.

The non-Spider-Man Sony movies featuring Venom (see "Tom Hardy to Star in 'Venom'") and Silver Sable and Black Cat (see "Spidey Spin-Off 'Silver and Black' Gets a Director") will not connect to the MCU, according to Feige, and Tom Holland as Spider-Man will not appear in the films, both Holland and Feige told the Toronto Sun.