The Upper Deck Company revealed Marvel Legendary: The Infinity Saga, a new expansion, which is currently on preorder with a release date of October 19, 2022.

This 31st expansion's theme revolves around the MCU’s Infinity Saga movies. The set adds new Heroes, Masterminds, Villains, and Schemes to the core set including Thanos and his Black Order. Cards showcase images for the Infinity Saga films, and the expansion's mechanics pair well with the Marvel Studios Phase 1 Base Set and the Spider-Man: Homecoming and Guardians of the Galaxy: Vol. 2 expansion sets.

The game box comes with 100 cards and a rulesheet. This game requires the core set to play and will retail for $25.00.

Upper Deck will release Marvel Legendary: Black Panther, a new expansion, into retail (see " 'Marvel Legendary: Black Panther'").