Born Aline Goldsmith in 1948, Kominsky-Crumb grew up on Long Island and studied art at the Cooper Union. She married Carl Kominsky in 1968 and moved with him to Tucson, Arizona. Her marriage was short-lived, but she earned her Bachelor of Fine Arts degree from the University of Arizona in 1971. While in Arizona she also met underground comics artists Spain Rodriguez and Kim Dietch, and she began drawing her own comics. She also decided to move to San Francisco, and she arrived in 1971, as Trina Robbins and others were forming the Wimmen's Comix collective. Her first comics story, “Goldie: A Neurotic Woman,” was included in Wimmen's Comix #1.Aline Crumb on Women Cartoonists”).
She and Noomin eventually broke with the Wimmen's Comix collective and created their own title, Twisted Sisters (see “R.I.P. Diane Noomin”). The first issue, with stories by both creators, was published by Last Gasp in 1976. In 1991 they put together an anthology of comics by Carol Tyler, Phoebe Glockner, Mary Fleener, and other women artists, titled Twisted Sisters: A Collection of Bad Girl Art, which was published by Viking Penguin and was nominated for an Eisner Award. In 1994 Kitchen Sink Press published a four-issue Twisted Sisters miniseries that was collected the following year as Twisted Sisters, Vol. 2: Drawing the Line.
In addition to creating comics, Kominsky-Crumb was the editor of the underground comic Weirdo from 1986 to 1993.
In addition to making comics, Kominsky-Crumb was a painter. “I also paint and I‘m a grandmother and I teach yoga and I have an art gallery so I’m really busy,” she told ICv2. The family moved to France in 1991, after which she spent more time on painting and less on comics, although she did mention in the interview that she was working on another book.
She is survived by her husband, Robert Crumb, and her daughter, Sophie Crumb, both of whom are also cartoonists.